PROGRAM OBJECTIVES:
To encourage basic and clinical biomedical research and research training for a greater understanding of diabetes and the underlying mechanisms that cause diabetes and related complications. Fundamental and clinical studies include the etiology, pathogenesis, prevention, diagnosis and treatment of diabetes mellitus and its complications. In endocrine research, to encourage biomedical research for a greater understanding of the normal and abnormal function of the pituitary, thyroid, parathyroid, adrenal, pineal, thymus glands, as well as the action of hormones, hormone biosynthesis, secretion, metabolism, binding to protein carriers and subsequent release, and the kinetics of binding. In metabolic research, to encourage basic studies on fundamental metabolic processes of diseases such as membrane structure, function, and transport phenomena enzyme biosynthesis; and basic and clinical studies on the etiology, pathogenesis, prevention, and treatment of inherited metabolic disorders (such as cystic fibrosis) as an example to support extramural basic laboratory research and clinical investigations and provide postdoctoral biomedical research training for individuals interested in careers in health sciences and fields related to these programs. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; To increase private sector commercialization of innovations derived from Federal research and development; to increase small business participation in Federal research and development and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer between small business concerns and research institutions to increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.

 ELIGIBLE FUNCTIONAL CATEGORIES:
1. HEALTH;
- Prevention and Control;
- Specialized Health Research and Training;

 WHO CAN BENEFIT FROM THIS PROGRAM:
- Public nonprofit institution/organization;
- Individual/Family;
- Private non-profit institution/organization;
- Student/Trainee;
- Graduate Student;
- Scientist/Researcher;
- U.S. Citizen;

 WHO CAN APPLY:
- State (includes District of Columbia, public institutions of higher education and hospitals);
- Local (includes State-designated Indian Tribes, excludes institutions of higher education and hospitals);
- Public non-profit institution/organization (includes institutions of higher education and hospitals);
- Individual/Family;
- Private non-profit institution/organization (includes institutions of higher education and hospitals);