PROGRAM OBJECTIVES:
To encourage basic and clinical biomedical research
and research training for a greater understanding of the basic and
clinical studies on normal abnormal function of the enteric nervous
system, on gastrointestinal hormones and peptides including their
structure, biological actions, receptors, release and correlation with
physiological events. Other studies include the action of drugs on
gastrointestinal motility, intestinal obstruction, the biochemistry of
contractile processes and diseases such as irritable bowel syndrome,
colonic diverticular disease, swallowing disorder, and gastro
esophageal reflux as well as studies on the process of food digestion
in the gastrointestinal tract; the assembly of digestive enzymes; the
growth and differentiation of gastrointestinal cells in normal and
disease states; and studies on gastrointestinal diseases such as
maldigestion and malabsorption syndromes, celiac sprue, diarrhea,
inflammatory bowel disease, and gastric and duodenal ulcers. To
encourage biomedical research and research training for a greater
understanding of the normal function and the diseases of the liver and
biliary tract including factors leading to liver cell injury, fibrosis,
and death; basic and applied studies on liver transplantation;
metabolism of bile acids and bilirubin; and factors controlling
cholesterol levels in bile as well as disease research on inborn errors
in bile metabolism hepatitis, and various liver diseases such as
Wilson's disease, primary biliary cirrhosis, and others. To encourage
biomedical research on the structure, function, and diseases of the
exocrine pancreas. To encourage biomedical research and research
training in obesity, anorexia, bulimia and other eating disorders, the
metabolism of nutrients and other dietary components at the organ,
cellular and subcellular levels in normal and diseased States. To
extramurally support basic laboratory research and clinical
investigations and provide postdoctoral biomedical research training
for individuals interested in careers in health sciences and fields
related to these programs. Small Business Innovation Research (SBIR)
program. To expand and improve the SBIR Program; to increase private
sector commercialization of innovations derived from Federal research
and development; to increase small business participation in Federal
research and development; and to foster and encourage participation of
socially and economically disadvantaged small business concerns and
women-owned small business concerns in technological innovation. Small
Business Technology Transfer (STTR) program: To stimulate and foster
scientific and technological innovation through cooperative research
and development carried out between small business concerns and
research institutions; to foster technology transfer between small
business concerns and research institutions to increase private sector
commercialization of innovations derived from Federal research and
development; and to foster and encourage participation of socially and
economically disadvantaged small business concerns and women-owned
small business concerns in technological innovation.
ELIGIBLE FUNCTIONAL CATEGORIES:
1. FOOD AND NUTRITION;
- Research;
2. HEALTH;
- Prevention and Control;
- Specialized Health Research and Training;
WHO CAN BENEFIT FROM THIS PROGRAM:
- Public nonprofit institution/organization;
- Individual/Family;
- Private non-profit institution/organization;
- Student/Trainee;
- Graduate Student;
- Scientist/Researcher;
- U.S. Citizen;
- Health Professional;
WHO CAN APPLY:
- State (includes District of Columbia, public institutions of higher education and hospitals);
- Local (includes State-designated Indian Tribes, excludes institutions of higher education and hospitals);
- Public non-profit institution/organization (includes institutions of higher education and hospitals);
- Individual/Family;
- Private non-profit institution/organization (includes institutions of higher education and hospitals);
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